The Unconquered

An Le, Hobart City High School

In collaboration with Kathryn Maskell, Menzies Institute for Medical Research, UTAS

Artist’s Statement

Imagine slowly losing control of your body – the simple tasks of daily life, like speaking, swallowing, or even breathing, becoming insurmountable challenges. Think about it for a moment. This is the harsh reality faced by those affected by amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. This devastating neurodegenerative disorder gradually robs individuals of their motor functions, leaving thousands of patients and their loved ones in a constant battle against the inevitable progression of muscle deterioration and the heartbreaking loss of independence and quality of life.

At first, I envisioned my artwork portraying the devastating impact of ALS. However, as I looked up stories and perspectives of the ALS community, I was struck by the remarkable resilience, determination and joy for life that so many patients exhibited, even in the face of overwhelming adversity. I shifted the focus of my work to celebrate the indomitable individuals who refuse to be defined or as represented in the name, conquered by their condition. 

My artwork will take you to a neural landscape, where the wire structures and lights guide you through the pathways of the human mind. I have elevated this concept by crafting a tree-like structure that symbolises the brain’s branching neurons and interconnected nature. While scientists continue to solve the mysteries of ALS, we know that changes in neuronal excitability and TDP-43 pathology play a crucial role in the degeneration of neurons. Changes in neuronal excitability can cause neurons to fire action potentials too much, or too little, in response to a stimulus. I have captured this through the flashing lights that represent the firing patterns of neurons. Despite the devastating nature of ALS, the patient’s facial expression in my artwork remains calm and peaceful, with a gentle smile gracing their features. The smile carries resilience and an appreciation for life’s preciousness.

Participating in Colab has been an enriching experience, allowing me to explore Kathryn’s research while enhancing various skills, from hands-on techniques like working with clay to transferable abilities such as time management and bridging the communication between art and science. The platform has allowed me to problem-solve and creatively represent my artistic vision. Moreover, interacting with scientists has opened my eyes to different perspectives and aspects of the world that I hadn’t previously encountered. As someone with a keen interest in science and creativity, this has been an incredible opportunity to grow, deepen my passions, and explore the intersection of my interests, expanding my horizons.

As an artist, I aim to offer a glimpse into Kathryn’s research and raise awareness about ALS. The strength and determination I’ve witnessed in those affected by this disease are a profound source of inspiration. Their stories remind us of the extraordinary strength and gratitude that can be found even in the face of the most devastating challenges. By shining a light on the essential work of dedicated scientists like Kathryn, I also strive to offer hope to all who engage with my creation.

Photographer: OI Studios

Description: My artwork will take you to a neural landscape, where the wire structures and lights guide you through the pathways of the human mind. I have elevated this concept by crafting a tree-like structure that symbolises the brain’s branching neurons and interconnected nature.